Historical Highlights

  • Biochemistry of Jamaican vomiting sickness disease
Current Research Highlights
 
Biochemistry of Jamaican vomiting sickness disease

1950's & 60's
  • Ingestion of the arillus of unripe ackee linked to Jamaican vomiting sickness
  • Structure of hypoglycin A elucidated
  • Effects of hypoglycin A on metabolism
  • Assay methodology for hypoglycin developed
  • Mode of action of hypoglycin A on the pyruvate carboxylase and Acyl CoA dehydrogenase
  • Researchers -Von Holt, E. V. Ellington, E. A. Kean, E. Morrison.

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